Consequently, that it “activates” the azide to possess nucleophilic attack (5)
Consequently, that it “activates” the azide to possess nucleophilic attack (5) Regarding after the step, N(1) displaces one of the ligands regarding 2nd Cu on the Cu-acetylide cutting-edge to make step three. Because of proximity and you will electronic facts, N(3) are now able to easily attack C(4) of the alkyne, ultimately causing good metallocycle…